Non-Disjunction in Meiosis: Formation of Trisomy and Monosomy
Non-Disjunction in Meiosis: Formation of Trisomy and Monosomy
Non-Disjunction in Meiosis: Formation of Trisomy and Monosomy
Non-Disjunction in Meiosis: Formation of Trisomy and Monosomy
- What is Non-Disjunction? Learn how failure of chromosome separation during meiosis I or II leads to aneuploidy.
- Mechanisms Explained: Clear visuals demonstrate non-disjunction at both meiotic stages, showing the formation of gametes with extra or missing chromosomes.
- Clinical Correlations: Understand the genetic basis of trisomy (e.g., Down syndrome) and monosomy (e.g., Turner syndrome).
- Causes of Error: Explore risk factors including maternal age, spindle defects, and chromosomal mispairing.